MOTS-C Peptide (20MG)
0What is MOTS-c?
The MOTS-c peptide is a 16-amino acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA. As part of a recently recognized class of mitochondrial signaling peptides, MOTS-c participates in regulating cellular and whole-body metabolism. Research in cellular and animal models has shown its roles in supporting insulin sensitivity, glucose utilization, and broader metabolic homeostasis. MOTS-c uniquely links mitochondrial genome signaling to whole-body metabolic ba
Frequently Asked Questions
What is MOTS-c?
The MOTS-c peptide is a 16-amino acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA. As part of a recently recognized class of mitochondrial signaling peptides, MOTS-c participates in regulating cellular and whole-body metabolism. Research in cellular and animal models has shown its roles in supporting insulin sensitivity, glucose utilization, and broader metabolic homeostasis. MOTS-c uniquely links mitochondrial genome signaling to whole-body metabolic ba
What is the MOTS-c peptide and where is it encoded?
The MOTS-c peptide is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA. Unlike traditional mitochondrial proteins involved in energy production, MOTS-c functions as a signaling peptide that regulates whole-body metabolism, influencing glucose utilization, energy expenditure, and insulin sensitivity.
What MOTS-c dosing was used in the mouse study?
The animal model used daily intraperitoneal dosing, typically 0.5 mg/kg/day during long-term high-fat diet experiments. Some mechanistic or short-term metabolic studies employed 5 mg/kg/day. These amounts represent mouse-model dosing only in controlled laboratory settings and cannot be converted to human usage or extrapolated outside of research contexts.